​Vaccinia Capping Enzyme

The capped structure at the 5' of mature mRNA, known as the m7GPPPN structure or methylguanosine cap, not only protects mRNA from RNase degradation and prolongs its half-life but also enhances its stability during translation, splicing, and nuclear export processes. The Vaccinia capping enzyme (VCE) developed by Biori integrates the necessary activities of mRNA triphosphatase, guanylyltransferase, and guanine-N7 methyltransferase, using S-adenosylmethionine (SAM) as the methyl donor. It directly adds the m7G cap structure to the 5' of mRNA. This cap structure is closely related to the stability, transport, and translation of mRNA, significantly improving the stability and translational efficiency of mRNA used for cellular validation and in vivo expression.

Product Spec.:

10 U/μL

• BP-E05 说明书

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