Ribonuclease R

Rnase R (Ribonuclease R) is a Mg -dependent ribonuclease that belongs to the RNR superfamily and is derived from E. coli. It cleaves linear RNA from the 3' to 5' direction, completely hydrolyzing it into dinucleotides and trinucleotides. It is not sensitive to circular RNA or double-stranded RNA and can be used for the production of specialized RNA structures such as circular RNA (circRNA), lariat RNA, double-stranded RNA with less than 7 nucleotides overhang at the 3' end, and complex structured tRNA. RNase R is commonly used in gene expression and alternative splicing studies to digest linear RNA and enrich circRNA or lariat RNA.

Product Spec.:

20 U/μL

• BP-E08 说明书

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