Home » Product » Biopharma » mRNA » IVT Enzymes » DNase I GMP-grade, GMP-BP-E04
Product Catalog
DNase I GMP-grade is an endonuclease used to digest single-stranded and double-stranded DNA. In IVT workflows, DNase I is commonly used for template DNA removal after transcription according to the validated protocol.
Features
- GMP-grade enzyme for in vitro transcription and mRNA manufacturing workflows.
- Instruction manual provides activity, storage, and quality-control information for the enzyme.
- Designed for use in RNA synthesis, template preparation, or post-transcriptional processing workflows as applicable.
Application
- In vitro transcription and mRNA process development workflows.
- Research or manufacturing workflows requiring the specified GMP-grade enzyme.
Components
| Components | GMP-BP-E04-200 | GMP-BP-E04-2 K | GMP-BP-E04-20 K |
|---|---|---|---|
| 200 U | 2 KU | 20 KU | |
| DNase I GMP-grade (2 U/uL) | 0.1mL | 1mL | 10mL |
| 10× DNase IReaction Buffer | 0.2mL | 2mL | 20mL |
Shipping and Storage
| Condition | Recommendation |
|---|---|
| Storage | Store at -20±5°C. |
| Shipping | Ship frozen on dry ice or with validated frozen cold-chain packaging that maintains the specified frozen storage condition. |
| Handling | Avoid repeated freeze-thaw cycles; mix thoroughly after thawing where applicable. |
Data
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