Resources & Insights
Technical guides and reagent insights from BIORI for molecular diagnostics, NGS, mRNA and biopharma QC.
Articles for each product line and service.
Biori10 min readSpiroplasma in Insect-Cell Bioprocesses: Risk and qPCR Detection
Spiroplasma testing for Sf9, High Five and S2 insect cell processes: how it differs from mycoplasma, culture vs qPCR, and what ChP, USP and Ph. Eur. expect.
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BioriA New Layer of Alzheimer’s Risk: Hybrid Long-Read and Short-Read Sequencing
Structural variants in Alzheimer's disease: how long-read discovery plus short-read genotyping in 3,190 people found a FAM193B CCG repeat that SNP arrays miss.
BioriPCR Extension Time: How to Set It for Your Polymerase and Amplicon Length
How to set PCR extension time: multiply amplicon length by your polymerase's rate per kb, then set extension temperature, long range PCR and final extension.
BioriHigh-Fidelity PCR: When to Reach for It, and When Standard Taq Is Enough
High fidelity PCR or standard Taq? When a proofreading polymerase matters, when Taq is enough, how fidelity is measured, and how to choose by application.
BioriSPRI Beads: Cleanup and Size Selection Ratio Table With Recovery Data
SPRI beads: ratio tables for cleanup and double-sided size selection, recovery data across ratios and inputs, and tips for long-read, FFPE and automated runs.
BioriEnd Repair and dA-Tailing: T4 PNK, T4 DNA Polymerase and Klenow
What T4 PNK, T4 DNA polymerase, Klenow and Klenow exo⁻ each do in end repair and dA-tailing, with reaction conditions, FFPE and cfDNA notes, and an FAQ.
BioriBeyond the Gene List: How Smart-seq3 Delivers Transcript-Level Single-Cell Insights
Smart-seq3 adds 5′ UMI counting to full-length single-cell RNA-seq: what it reveals, how it works, Smart-seq3xpress scaling, and the enzymes behind each step.
BioriSPARK-seq (Science 2026): Single-Cell CRISPR Screens for Aptamer Discovery
SPARK-seq (Science 2026) pairs CRISPR knockout pools with single-cell multiomics for aptamer discovery, mapping 5,535 aptamers to 8 membrane proteins.
BioriBuild Your Workflow Your Way: Modular Enzymes & Comprehensive Kits for Multi-Platform, Multi-Gen Sequencing
AcuGenix NGS library prep enzymes and modules for standard library prep, tNGS multiplex PCR and single-cell cDNA, with benchmark data vs. leading suppliers.
BioriFrom Sanger to Long-Read Sequencing: A Technical Comparison of First-, Second- and Third-Generation Sequencing Technologies
Compare Sanger, NGS and long-read sequencing (PacBio HiFi, Oxford Nanopore): principles, read length, accuracy, throughput, cost and how to choose.
BioriMycoplasma qPCR Testing for Biologics
Learn how to evaluate mycoplasma qPCR testing for biologics, including LoD, target coverage, matrix suitability, controls, and Spiroplasma detection.
BioriResidual Host Cell DNA Testing by qPCR: Choosing CHO or E. coli Assays
Learn how residual host cell DNA testing by qPCR differs for CHO and E. coli workflows, and how to assess LoD, LoQ, linearity, recovery, and controls.
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