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Life Science Research

Articles from BIORI tagged “Life Science Research”. Guides, reagent insights and news across molecular diagnostics, NGS, mRNA and biopharma QC.

NGS & genomicsalzheimers structural variants long read cover

A New Layer of Alzheimer’s Risk: Hybrid Long-Read and Short-Read Sequencing

Structural variants in Alzheimer's disease: how long-read discovery plus short-read genotyping in 3,190 people found a FAM193B CCG repeat that SNP arrays miss.

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Life science researchpcr extension time polymerase cover

PCR Extension Time: How to Set It for Your Polymerase and Amplicon Length

How to set PCR extension time: multiply amplicon length by your polymerase's rate per kb, then set extension temperature, long range PCR and final extension.

17 min readRead
Life science researchproofreading polymerase dna cover

High-Fidelity PCR: When to Reach for It, and When Standard Taq Is Enough

High fidelity PCR or standard Taq? When a proofreading polymerase matters, when Taq is enough, how fidelity is measured, and how to choose by application.

13 min readRead
NGS & genomicssmart seq3 full length single cell rna seq cover

Beyond the Gene List: How Smart-seq3 Delivers Transcript-Level Single-Cell Insights

Smart-seq3 adds 5′ UMI counting to full-length single-cell RNA-seq: what it reveals, how it works, Smart-seq3xpress scaling, and the enzymes behind each step.

11 min readRead
NGS & genomicsspark seq cell selex aptamer cover

SPARK-seq (Science 2026): Single-Cell CRISPR Screens for Aptamer Discovery

SPARK-seq (Science 2026) pairs CRISPR knockout pools with single-cell multiomics for aptamer discovery, mapping 5,535 aptamers to 8 membrane proteins.

8 min readRead
Life science researchLab Indonesia 2026Past event

BIORI Biotech to Exhibit at Lab Indonesia 2026

BIORI Biotech will participate in Lab Indonesia 2026 at Booth 5D37, presenting innovative products and services for life science research, biotherapeutic analytical workflows, and molecular diagnostic product development.

2 min readRead
Molecular diagnosticsqPCR Results Analysis

qPCR Results Analysis: Amplification Curves, Melt Curves and Ct Values

How to interpret qPCR results: check controls, read amplification plots and Ct (Cq) values, troubleshoot curves and melt peaks, and calculate efficiency and ΔΔCt.

19 min readRead
Molecular diagnostics12 Golden Rules for PCR Primer Design

12 Golden Rules for PCR Primer Design

Use 12 practical PCR primer design rules to improve specificity, amplification efficiency and assay reliability while reducing dimers and off-target products.

5 min readRead
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