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NGS Library Prep

Articles from BIORI tagged “NGS Library Prep”. Guides, reagent insights and news across molecular diagnostics, NGS, mRNA and biopharma QC.

NGS & genomicsalzheimers structural variants long read cover

A New Layer of Alzheimer’s Risk: Hybrid Long-Read and Short-Read Sequencing

Structural variants in Alzheimer's disease: how long-read discovery plus short-read genotyping in 3,190 people found a FAM193B CCG repeat that SNP arrays miss.

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NGS & genomicsspri beads cover

SPRI Beads: Cleanup and Size Selection Ratio Table With Recovery Data

SPRI beads: ratio tables for cleanup and double-sided size selection, recovery data across ratios and inputs, and tips for long-read, FFPE and automated runs.

12 min readRead
NGS & genomicsend repair da tailing enzymes cover

End Repair and dA-Tailing: T4 PNK, T4 DNA Polymerase and Klenow

What T4 PNK, T4 DNA polymerase, Klenow and Klenow exo⁻ each do in end repair and dA-tailing, with reaction conditions, FFPE and cfDNA notes, and an FAQ.

12 min readRead
NGS & genomicssmart seq3 full length single cell rna seq cover

Beyond the Gene List: How Smart-seq3 Delivers Transcript-Level Single-Cell Insights

Smart-seq3 adds 5′ UMI counting to full-length single-cell RNA-seq: what it reveals, how it works, Smart-seq3xpress scaling, and the enzymes behind each step.

11 min readRead
NGS & genomicsngs library prep enzymes modules cover

Build Your Workflow Your Way: Modular Enzymes & Comprehensive Kits for Multi-Platform, Multi-Gen Sequencing

AcuGenix NGS library prep enzymes and modules for standard library prep, tNGS multiplex PCR and single-cell cDNA, with benchmark data vs. leading suppliers.

14 min readRead
NGS & genomicsfirst second third generation sequencing cover

From Sanger to Long-Read Sequencing: A Technical Comparison of First-, Second- and Third-Generation Sequencing Technologies

Compare Sanger, NGS and long-read sequencing (PacBio HiFi, Oxford Nanopore): principles, read length, accuracy, throughput, cost and how to choose.

15 min readRead
Molecular diagnosticsBIORI MEDICA 2026 Hall 3 Booth K72 5BUpcoming · Nov 16–19, 2026

Meet BIORI at MEDICA 2026 in Düsseldorf | Hall 3, Booth K72-5B

BIORI will exhibit at MEDICA 2026 in Düsseldorf, Germany, on 16–19 November. Visit Hall 3, Booth K72-5B to discuss IVD raw materials, lyophilization services and biopharma QC solutions.

2 min readRead
Molecular diagnosticsblood based molecular profiling reagent strategy cover

Blood-Based Molecular Profiling Reagent Strategy for Diagnostics

Caris’ NYSDOH application for a blood-based molecular profiling test highlights reagent and QC priorities for cfDNA extraction, NGS library prep, qPCR verification and OEM diagnostics.

6 min readRead
Molecular diagnosticspharmacogenomic testing reagent strategy clinical diagnostics cover

Pharmacogenomic Testing Reagent Strategy for Clinical Diagnostics

Foundation Medicine’s new collaboration with Fulgent Genetics highlights rising clinical demand for pharmacogenomic testing. This guide explains reagent, QC and OEM considerations for diagnostic teams.

4 min readRead
Molecular diagnosticscfdna mrd testing reagent qc guide cover

cfDNA MRD Testing Reagent Strategy for Molecular Diagnostics

CareDx’s Naveris acquisition highlights rising interest in cfDNA MRD testing. This guide explains reagent, assay QC, sample prep and OEM considerations for molecular diagnostics teams.

5 min readRead
NGS & genomicsngs sample prep reagent strategy qc codex cover

NGS Sample Preparation for Molecular Diagnostics: Reagent Strategy and QC

A practical guide to NGS sample preparation for molecular diagnostics, covering input QC, library prep reagent selection, workflow consistency, and OEM considerations.

5 min readRead
Molecular diagnosticsbiori bio korea 2026 booth l13 coverPast event

Meet BIORI at BIO KOREA 2026 — Visit Booth L13

BIORI will attend BIO KOREA 2026 in Seoul from April 28–30. Visit us at Booth L13 to discuss IVD raw materials, PCR, NGS, IVT, OEM, and biopharma QC solutions.

4 min readRead
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