Sequencing Reagents
Articles from BIORI tagged “Sequencing Reagents”. Guides, reagent insights and news across molecular diagnostics, NGS, mRNA and biopharma QC.
Articles for each product line and service.
BioriResources & Insights9 min readA New Layer of Alzheimer’s Risk: Hybrid Long-Read and Short-Read Sequencing
Structural variants in Alzheimer's disease: how long-read discovery plus short-read genotyping in 3,190 people found a FAM193B CCG repeat that SNP arrays miss.
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BioriResources & InsightsSPRI Beads: Cleanup and Size Selection Ratio Table With Recovery Data
SPRI beads: ratio tables for cleanup and double-sided size selection, recovery data across ratios and inputs, and tips for long-read, FFPE and automated runs.
BioriResources & InsightsEnd Repair and dA-Tailing: T4 PNK, T4 DNA Polymerase and Klenow
What T4 PNK, T4 DNA polymerase, Klenow and Klenow exo⁻ each do in end repair and dA-tailing, with reaction conditions, FFPE and cfDNA notes, and an FAQ.
BioriResources & InsightsSPARK-seq (Science 2026): Single-Cell CRISPR Screens for Aptamer Discovery
SPARK-seq (Science 2026) pairs CRISPR knockout pools with single-cell multiomics for aptamer discovery, mapping 5,535 aptamers to 8 membrane proteins.
BioriResources & InsightsBuild Your Workflow Your Way: Modular Enzymes & Comprehensive Kits for Multi-Platform, Multi-Gen Sequencing
AcuGenix NGS library prep enzymes and modules for standard library prep, tNGS multiplex PCR and single-cell cDNA, with benchmark data vs. leading suppliers.
BioriResources & InsightsFrom Sanger to Long-Read Sequencing: A Technical Comparison of First-, Second- and Third-Generation Sequencing Technologies
Compare Sanger, NGS and long-read sequencing (PacBio HiFi, Oxford Nanopore): principles, read length, accuracy, throughput, cost and how to choose.
BioriResources & InsightsBlood-Based Molecular Profiling Reagent Strategy for Diagnostics
Caris’ NYSDOH application for a blood-based molecular profiling test highlights reagent and QC priorities for cfDNA extraction, NGS library prep, qPCR verification and OEM diagnostics.
BioriResources & InsightsPharmacogenomic Testing Reagent Strategy for Clinical Diagnostics
Foundation Medicine’s new collaboration with Fulgent Genetics highlights rising clinical demand for pharmacogenomic testing. This guide explains reagent, QC and OEM considerations for diagnostic teams.
BioriResources & InsightsNGS Sample Preparation for Molecular Diagnostics: Reagent Strategy and QC
A practical guide to NGS sample preparation for molecular diagnostics, covering input QC, library prep reagent selection, workflow consistency, and OEM considerations.
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